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Huffington Foundation Endowed Chair in Aging; Director, Huffington Center on Aging; Professor, Departments of Molecular and Human Genetics, Baylor College of Medicine

Cure Alzheimer’s Fund Research Leadership Group

Hui Zheng is interested in understanding how cells in our brain clear unwanted materials, and how this system declines with aging to contribute to Alzheimer’s disease.  

Simply stated, Dr. Zheng and her lab are looking for ways to elevate the cell’s natural garbage disposal system and, more specifically, ways to clear the protein aggregates that accumulate in the brains of individuals with Alzheimer’s disease. Learning more about the system is a driver for Dr. Zheng and her team to develop therapies that are effective and safe. 

“Alzheimer’s disease affects the brain. There is so much that we still do not know about how the brain works in normal and disease conditions. Understanding how the brain changes with aging will help in developing therapeutic interventions. Learning more about the brain keeps me motivated. 

“Cure Alzheimer’s Fund allows us to initiate a new project related to lipid signaling in immune system regulation. We have been able to generate some exciting data in the past year, and we are expanding the project to both investigating the mechanisms and exploring therapeutic targeting.” 

To learn more about the Zheng Lab, click here