Director, Helen and Robert Appel Alzheimer’s Disease Research Institute and Burton P. and Judith B. Resnick Distinguished Professor in Neurodegenerative Diseases, Weill Cornell Medicine
Cure Alzheimer’s Fund Research Leadership Group
Li Gan is a force in the fight against Alzheimer’s disease. Dr. Gan’s team explores converging pathways in neurodegenerative diseases, particularly the accumulation and trafficking of toxic proteins and the abnormal activation of innate immune responses. Her lab has identified new mechanisms by which abnormal signaling in microglia impairs neuronal function, and discovered that Alzheimer’s-associated increases in acetylation of the protein tau lead to tau accumulation and toxicity. This data resulted in two Phase 1 clinical trials.
To learn more about the Gan Lab, click here.