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The Research

“Understanding the role of sex in health and disease is a cornerstone of personalized medicine. The high failure rate of clinical drug trials in Alzheimer’s disease (AD) over the past decade has increased the urgency to better dissect the heterogeneity of AD in order to facilitate more personalized therapies. ”

Females have been noted to be at the epicenter of the AD epidemic due to the fact that they account for roughly two-thirds of AD patients in the US and also the majority of caregivers. However, despite substantial research investment in AD over decades, the biological role of sex in the neurodegenerative process has been relatively understudied…” *

*Sex Differences in Cognitive Decline in Subjects with High Likelihood of Mild Cognitive Impairment due to Alzheimer’s disease. Murali Doraiswamy, Ph.D., member of the Cure Alzheimer’s Fund Research Leadership Group and Rudolph Tanzi, Ph.D., Chair of the Cure Alzheimer’s Fund Research Leadership group, Scientific Reports, 2018.

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