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The Pathology of Alzheimer’s Disease

The human brain contains tens of billions of neurons– specialized cells that process and transmit information via electrical and chemical signals.

They send messages between the different parts of the brain, and from the brain to the muscles and organs of the human body. Many molecular and cellular changes and disruptions occur in the brain of a person with Alzheimer’s disease, and research suggests that the pathology causing these disruptions begin to develop 20 years before the first symptoms appear. These changes can be observed in brain tissue under the microscope upon autopsy.